Rodney (Michael Vartan) and Mike (Sean Astin of THE LORD OF THE RINGS) are a pair of irresponsible, hard-partying corporate tire salesmen. But when their beloved boss dies after a wild night at a strip club, the dweeb colleague (David Cross of ARRESTED DEVELOPMENT) they've been tormenting for years gets promoted to the top position. And for his first order of business, hell demote Rodney and Mike to the female secretarial pool. Can two chauvinist pranksters now find a way to become one of the girls as well as sensitive guys, all while plotting the ultimate revenge against a nerd-turned-tyrant?